Summary for 1VSN
Entry DOI | 10.2210/pdb1vsn/pdb |
Descriptor | Cathepsin K, N-(2-AMINOETHYL)-N~2~-{(1S)-1-[4'-(AMINOSULFONYL)BIPHENYL-4-YL]-2,2,2-TRIFLUOROETHYL}-L-LEUCINAMIDE (3 entities in total) |
Functional Keywords | osteoporosis, structure-guided drug design, proteae, hydrolase |
Biological source | Homo sapiens (human) |
Total number of polymer chains | 1 |
Total formula weight | 23517.27 |
Authors | McGrath, M. (deposition date: 2007-03-19, release date: 2007-04-24, Last modification date: 2023-12-27) |
Primary citation | Li, C.S.,Deschenes, D.,Desmarais, S.,Falgueyret, J.P.,Gauthier, J.Y.,Kimmel, D.B.,McGrath, M.E.,McKay, D.J.,Percival, M.D.,Riendeau, D.,Rodan, S.B.,Truong, V.L.,Wesolowski, G.,Zamboni, R.,Black, W.C. Identification of a potent and selective non-basic cathepsin K inhibitor. Bioorg.Med.Chem.Lett., 16:1985-1989, 2006 Cited by PubMed: 16413777DOI: 10.1016/j.bmcl.2005.12.071 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2 Å) |
Structure validation
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