1VJ7

Crystal structure of the bifunctional catalytic fragment of RelSeq, the RelA/SpoT homolog from Streptococcus equisimilis.

1VJ7 の概要

• エントリーDOI: 10.2210/pdb1vj7/pdb
• 分子名称: Bifunctional RELA/SPOT, MANGANESE (II) ION, GUANOSINE-5'-DIPHOSPHATE, ... (5 entities in total)
• 機能のキーワード: hd domain, alpha beta 2-layer sandwich, helix bundle, manganese, gdp, ppg2':3'p, (p)ppgpp, ppgpp, rela, spot, stringent response, stringent factor, stringent effector, magic spot, rsh, hydrolase, transferase
• 由来する生物種: Streptococcus dysgalactiae subsp. equisimilis
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 92714.15

構造登録者

Hogg, T.,Mechold, U.,Malke, H.,Cashel, M.,Hilgenfeld, R. (登録日: 2004-02-03, 公開日: 2004-05-04, 最終更新日: 2024-02-14)

• 主引用文献: Hogg, T.,Mechold, U.,Malke, H.,Cashel, M.,Hilgenfeld, R.; Conformational antagonism between opposing active sites in a bifunctional RelA/SpoT homolog modulates (p)ppGpp metabolism during the stringent response.; Cell(Cambridge,Mass.), 117:57-68, 2004; PubMed: 15066282; DOI: 10.1016/S0092-8674(04)00260-0

実験手法

X-RAY DIFFRACTION (2.1 Å)