1UMD

branched-chain 2-oxo acid dehydrogenase (E1) from Thermus thermophilus HB8 with 4-methyl-2-oxopentanoate as an intermediate

Summary for 1UMD

Related1UM9 1UMB 1UMC
Descriptor2-oxo acid dehydrogenase alpha subunit, 2-oxo acid dehydrogenase beta subunit, MAGNESIUM ION, ... (6 entities in total)
Functional Keywordsalpha(2)beta(2) tetramer, structural genomics, riken structural genomics/proteomics initiative, rsgi, oxidoreductase
Biological sourceThermus thermophilus
Total number of polymer chains4
Total molecular weight154534.72
Authors
Nakai, T.,Nakagawa, N.,Maoka, N.,Masui, R.,Kuramitsu, S.,Kamiya, N.,RIKEN Structural Genomics/Proteomics Initiative (RSGI) (deposition date: 2003-09-25, release date: 2004-03-30, Last modification date: 2011-07-13)
Primary citation
Nakai, T.,Nakagawa, N.,Maoka, N.,Masui, R.,Kuramitsu, S.,Kamiya, N.
Ligand-induced Conformational Changes and a Reaction Intermediate in Branched-chain 2-Oxo Acid Dehydrogenase (E1) from Thermus thermophilus HB8, as Revealed by X-ray Crystallography
J.Mol.Biol., 337:1011-1033, 2004
PubMed: 15033367 (PDB entries with the same primary citation)
DOI: 10.1016/j.jmb.2004.02.011
MImport into Mendeley
Experimental method
X-RAY DIFFRACTION (1.9 Å)
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Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers0.19570.4%1.5%2.6%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution
Download full validation report