1UKI
Structural basis for the selective inhibition of JNK1 by the scaffolding protein JIP1 and SP600125
Summary for 1UKI
Entry DOI | 10.2210/pdb1uki/pdb |
Related | 1UKH |
Descriptor | mitogen-activated protein kinase 8 isoform 4, 11-mer peptide from C-jun-amino-terminal kinase interacting protein 1, 2,6-DIHYDROANTHRA/1,9-CD/PYRAZOL-6-ONE, ... (4 entities in total) |
Functional Keywords | transferase, phosphorylation |
Biological source | Homo sapiens (human) More |
Cellular location | Cytoplasm (By similarity): Q9WVI9 |
Total number of polymer chains | 2 |
Total formula weight | 44154.03 |
Authors | Heo, Y.-S.,Kim, Y.K.,Sung, B.-J.,Lee, H.S.,Lee, J.I.,Seo, C.I.,Park, S.-Y.,Kim, J.H.,Hyun, Y.-L.,Jeon, Y.H.,Ro, S.,Lee, T.G.,Cho, J.M.,Hwang, K.Y.,Yang, C.-H. (deposition date: 2003-08-23, release date: 2004-08-30, Last modification date: 2023-12-27) |
Primary citation | Heo, Y.-S.,Kim, S.K.,Seo, C.I.,Kim, Y.K.,Sung, B.-J.,Lee, H.S.,Lee, J.I.,Park, S.-Y.,Kim, J.H.,Hwang, K.Y.,Hyun, Y.-L.,Jeon, Y.H.,Ro, S.,Cho, J.M.,Lee, T.G.,Yang, C.-H. Structural basis for the selective inhibition of JNK1 by the scaffolding protein JIP1 and SP600125 Embo J., 23:2185-2195, 2004 Cited by PubMed: 15141161DOI: 10.1038/sj.emboj.7600212 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.7 Å) |
Structure validation
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