1UC6

Solution Structure of the Carboxyl Terminal Domain of the Ciliary Neurotrophic Factor Receptor

Summary for 1UC6

• Entry DOI: 10.2210/pdb1uc6/pdb
• Descriptor: Ciliary Neurotrophic Factor Receptor alpha (1 entity in total)
• Functional Keywords: cytokine, ciliary neurotrophic factor, leukemia inhibitory factor, cytokine receptor, fibronectin type iii domain-like topology, seven beta-strands, two anti-parallel beta-sheets, protein binding
• Biological source: Homo sapiens (human)
• Cellular location: Cell membrane; Lipid-anchor, GPI-anchor: P26992
• Total number of polymer chains: 1
• Total formula weight: 12333.68

Authors

Man, D.,He, W.,Sze, K.H.,Ke, G.,Smith, D.K.,Ip, N.Y.,Zhu, G. (deposition date: 2003-04-08, release date: 2004-08-10, Last modification date: 2023-12-27)

• Primary citation: Man, D.,He, W.,Sze, K.H.,Gong, K.,Smith, D.K.,Zhu, G.,Ip, N.Y.; Solution structure of the C-terminal domain of the ciliary neurotrophic factor (CNTF) receptor and ligand free associations among components of the CNTF receptor complex; J.Biol.Chem., 278:23285-23294, 2003; PubMed: 12707266; DOI: 10.1074/jbc.M301976200

Experimental method