1U6A

Crystal Structure of the Broadly Neutralizing Anti-HIV Fab F105

Summary for 1U6A

• Entry DOI: 10.2210/pdb1u6a/pdb
• Descriptor: F105 LIGHT CHAIN, F105 HEAVY CHAIN (3 entities in total)
• Functional Keywords: immunoglobulin, fab, f105, gp120, hiv, immune system
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 2
• Total formula weight: 47252.73

Authors

Wilkinson, R.A.,Piscitelli, C.,Teintze, M.,Lawrence, C.M. (deposition date: 2004-07-29, release date: 2005-08-09, Last modification date: 2023-08-23)

• Primary citation: Wilkinson, R.A.,Piscitelli, C.,Teintze, M.,Cavacini, L.A.,Posner, M.R.,Lawrence, C.M.; Structure of the Fab fragment of F105, a broadly reactive anti-human immunodeficiency virus (HIV) antibody that recognizes the CD4 binding site of HIV type 1 gp120.; J.Virol., 79:13060-13069, 2005; PubMed: 16189008; DOI: 10.1128/JVI.79.20.13060-13069.2005

Experimental method

X-RAY DIFFRACTION (2.81 Å)