1U59

Crystal Structure of the ZAP-70 Kinase Domain in Complex with Staurosporine

Summary for 1U59

Entry DOI	10.2210/pdb1u59/pdb
Descriptor	Tyrosine-protein kinase ZAP-70, STAUROSPORINE (3 entities in total)
Functional Keywords	transferase
Biological source	Homo sapiens (human)
Cellular location	Cytoplasm : P43403
Total number of polymer chains	1
Total formula weight	33714.13
Authors	Jin, L.,Pluskey, S.,Petrella, E.C.,Cantin, S.M.,Gorga, J.C.,Rynkiewicz, M.J.,Pandey, P.,Strickler, J.E.,Babine, R.E.,Weaver, D.T.,Seidl, K.J. (deposition date: 2004-07-27, release date: 2004-08-17, Last modification date: 2023-08-23)
Primary citation	Jin, L.,Pluskey, S.,Petrella, E.C.,Cantin, S.M.,Gorga, J.C.,Rynkiewicz, M.J.,Pandey, P.,Strickler, J.E.,Babine, R.E.,Weaver, D.T.,Seidl, K.J. The Three-dimensional Structure of the ZAP-70 Kinase Domain in Complex with Staurosporine: IMPLICATIONS FOR THE DESIGN OF SELECTIVE INHIBITORS J.Biol.Chem., 279:42818-42825, 2004 Cited by PubMed: 15292186 DOI: 10.1074/jbc.M407096200 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.3 Å)

Structure validation