1U4R

Crystal Structure of human RANTES mutant 44-AANA-47

Summary for 1U4R

• Entry DOI: 10.2210/pdb1u4r/pdb
• Related: 1b3a 1eqt 1u4l 1u4m 1u4p
• Descriptor: Small inducible cytokine A5, SULFATE ION (3 entities in total)
• Functional Keywords: chemoattractant, cytokine, chemokine, rantes, mutant, glycosaminoglycan, protein-heparin disaccharide complex, attractant
• Biological source: Homo sapiens (human)
• Cellular location: Secreted: P13501
• Total number of polymer chains: 4
• Total formula weight: 30814.89

Authors

Shaw, J.P.,Johnson, Z.,Borlat, F.,Zwahlen, C.,Kungl, A.,Roulin, K.,Harrenga, A.,Wells, T.N.C.,Proudfoot, A.E.I. (deposition date: 2004-07-26, release date: 2004-11-09, Last modification date: 2023-08-23)

• Primary citation: Shaw, J.P.,Johnson, Z.,Borlat, F.,Zwahlen, C.,Kungl, A.,Roulin, K.,Harrenga, A.,Wells, T.N.,Proudfoot, A.E.; The X-ray structure of RANTES: heparin-derived disaccharides allows the rational design of chemokine inhibitors.; Structure, 12:2081-2093, 2004; PubMed: 15530372; DOI: 10.1016/j.str.2004.08.014

Experimental method

X-RAY DIFFRACTION (2.2 Å)