1U0W

An Aldol Switch Discovered in Stilbene Synthases Mediates Cyclization Specificity of Type III Polyketide Synthases: 18xCHS+resveratrol Structure

1U0W の概要

• エントリーDOI: 10.2210/pdb1u0w/pdb
• 関連するPDBエントリー: 1BI5 1U0U 1U0V
• 分子名称: Chalcone synthase 2, RESVERATROL (3 entities in total)
• 機能のキーワード: type iii polyketide synthase, pks, condensing enzyme, thiolase fold, alpha-beta-alpha-beta-alpha fold, aldol switch, catalytic triad, engineered resveratrol synthase, rs, sts, chs, chalcone synthase, stilbene synthase, transferase
• 由来する生物種: Medicago sativa
• タンパク質・核酸の鎖数: 4
• 化学式量合計: 172410.27

構造登録者

Austin, M.B.,Bowman, M.E.,Ferrer, J.-L.,Schroder, J.,Noel, J.P. (登録日: 2004-07-14, 公開日: 2004-10-12, 最終更新日: 2023-08-23)

• 主引用文献: Austin, M.B.,Bowman, M.E.,Ferrer, J.-L.,Schroder, J.,Noel, J.P.; An Aldol Switch Discovered in Stilbene Synthases Mediates Cyclization Specificity of Type III Polyketide Synthases; Chem.Biol., 11:1179-1194, 2004; PubMed: 15380179; DOI: 10.1016/j.chembiol.2004.05.024

実験手法

X-RAY DIFFRACTION (2 Å)