1TW7
Wide Open 1.3A Structure of a Multi-drug Resistant HIV-1 Protease Represents a Novel Drug Target
Summary for 1TW7
Entry DOI | 10.2210/pdb1tw7/pdb |
Related | 1RPI 1RQ9 1RV7 |
Descriptor | protease, SODIUM ION (3 entities in total) |
Functional Keywords | hiv protease, aids, polyprotein, hydrolase, aspartyl protease, multi-drug resistance |
Biological source | Human immunodeficiency virus 1 |
Total number of polymer chains | 2 |
Total formula weight | 21525.20 |
Authors | Martin, P.,Vickrey, J.F.,Proteasa, G.,Jimenez, Y.L.,Wawrzak, Z.,Winters, M.A.,Merigan, T.C.,Kovari, L.C. (deposition date: 2004-06-30, release date: 2005-07-19, Last modification date: 2023-08-23) |
Primary citation | Martin, P.,Vickrey, J.F.,Proteasa, G.,Jimenez, Y.L.,Wawrzak, Z.,Winters, M.A.,Merigan, T.C.,Kovari, L.C. Wide Open 1.3A Structure of a Multi-drug Resistant HIV-1 Protease Represents a Novel Drug Target Structure, 13:1887-1895, 2005 Cited by PubMed: 16338417DOI: 10.1016/j.str.2005.11.005 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.3 Å) |
Structure validation
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