1TV5

Plasmodium falciparum dihydroorotate dehydrogenase with a bound inhibitor

1TV5 の概要

• エントリーDOI: 10.2210/pdb1tv5/pdb
• 分子名称: Dihydroorotate dehydrogenase homolog, mitochondrial, SULFATE ION, (2Z)-2-cyano-3-hydroxy-N-[4-(trifluoromethyl)phenyl]but-2-enamide, ... (7 entities in total)
• 機能のキーワード: alpha-beta barrel; tim barrel, oxidoreductase
• 由来する生物種: Plasmodium falciparum (malaria parasite P. falciparum)
• 細胞内の位置: Mitochondrion inner membrane (By similarity); Single-pass membrane protein (Potential): Q08210
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 51939.95

構造登録者

Hurt, D.E.,Widom, J.,Clardy, J. (登録日: 2004-06-27, 公開日: 2005-09-06, 最終更新日: 2023-08-23)

• 主引用文献: Hurt, D.E.,Widom, J.,Clardy, J.; Structure of Plasmodium falciparum dihydroorotate dehydrogenase with a bound inhibitor.; Acta Crystallogr.,Sect.D, 62:312-323, 2006; PubMed: 16510978; DOI: 10.1107/S0907444905042642

実験手法

X-RAY DIFFRACTION (2.4 Å)