1TSQ
CRYSTAL STRUCTURE OF AP2V SUBSTRATE VARIANT OF NC-P1 DECAMER PEPTIDE IN COMPLEX WITH V82A/D25N HIV-1 PROTEASE MUTANT
Summary for 1TSQ
Entry DOI | 10.2210/pdb1tsq/pdb |
Descriptor | Pol polyprotein, AP2V NC-P1 SUBSTRATE PEPTIDE, ACETATE ION, ... (4 entities in total) |
Functional Keywords | co-evolution, nucleocapdis, substrate recognition, hiv-1 protease, hydrolase-viral protein complex, hydrolase/viral protein |
Total number of polymer chains | 3 |
Total formula weight | 23326.28 |
Authors | Prabu-Jeyabalan, M.,Nalivaika, E.A.,King, N.M.,Schiffer, C.A. (deposition date: 2004-06-21, release date: 2005-03-29, Last modification date: 2023-08-23) |
Primary citation | Prabu-Jeyabalan, M.,Nalivaika, E.A.,King, N.M.,Schiffer, C.A. Structural basis for coevolution of a human immunodeficiency virus type 1 nucleocapsid-p1 cleavage site with a V82A drug-resistant mutation in viral protease J.Virol., 78:12446-12454, 2004 Cited by PubMed: 15507631DOI: 10.1128/JVI.78.22.12446-12454.2004 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2 Å) |
Structure validation
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