1TR7

FimH adhesin receptor binding domain from uropathogenic E. coli

Summary for 1TR7

• Entry DOI: 10.2210/pdb1tr7/pdb
• Related: 1UWF
• Descriptor: FimH protein, butyl alpha-D-mannopyranoside, CACODYLATE ION, ... (5 entities in total)
• Functional Keywords: type-1 pili, adhesion, urinary tract infections, uropathogenic e. coli, carbohydrate binding, cell adhesion
• Biological source: Escherichia coli
• Cellular location: Fimbrium: P08191
• Total number of polymer chains: 2
• Total formula weight: 36219.10

Authors

Bouckaert, J.,Berglund, J.,Schembri, M.,De Genst, E.,Cools, L.,Wuhrer, M.,Hung, C.S.,Pinkner, J.,Slattegard, R.,Zavialov, A.,Choudhury, D.,Langermann, S.,Hultgren, S.J.,Wyns, L.,Klemm, P.,Oscarson, S.,Knight, S.D.,De Greve, H. (deposition date: 2004-06-21, release date: 2005-05-03, Last modification date: 2023-10-25)

• Primary citation: Bouckaert, J.,Berglund, J.,Schembri, M.,De Genst, E.,Cools, L.,Wuhrer, M.,Hung, C.S.,Pinkner, J.,Slattegard, R.,Zavialov, A.,Choudhury, D.,Langermann, S.,Hultgren, S.J.,Wyns, L.,Klemm, P.,Oscarson, S.,Knight, S.D.,De Greve, H.; Receptor binding studies disclose a novel class of high-affinity inhibitors of the Escherichia coli FimH adhesin; Mol.Microbiol., 55:441-455, 2005; PubMed: 15659162; DOI: 10.1111/j.1365-2958.2004.04415.x

Experimental method

X-RAY DIFFRACTION (2.1 Å)