1TQC
Ovine recombinant PrP(114-234), ARR variant in complex with the VRQ14 Fab fragment (IgG2a)
Summary for 1TQC
Entry DOI | 10.2210/pdb1tqc/pdb |
Related | 1TQB |
Descriptor | prion protein, VRQ14 Fab Heavy chain, VRQ14 Fab light chain, ... (4 entities in total) |
Functional Keywords | prion, antibody, unknown function-immune system complex, unknown function/immune system |
Biological source | Ovis aries (sheep) More |
Cellular location | Cell membrane; Lipid-anchor, GPI-anchor: P23907 |
Total number of polymer chains | 3 |
Total formula weight | 59163.89 |
Authors | Eghiaian, F.,Grosclaude, J.,Lesceu, S.,Debey, P.,Doublet, B.,Treguer, E.,Rezaei, H.,Knossow, M. (deposition date: 2004-06-17, release date: 2004-07-06, Last modification date: 2011-07-13) |
Primary citation | Eghiaian, F.,Grosclaude, J.,Lesceu, S.,Debey, P.,Doublet, B.,Treguer, E.,Rezaei, H.,Knossow, M. Insight into the PrPC-->PrPSc conversion from the structures of antibody-bound ovine prion scrapie-susceptibility variants Proc.Natl.Acad.Sci.USA, 101:10254-10259, 2004 Cited by PubMed: 15240887DOI: 10.1073/pnas.0400014101 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.8 Å) |
Structure validation
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