1TP7
Crystal Structure of the RNA-dependent RNA Polymerase from Human Rhinovirus 16
Summary for 1TP7
Entry DOI | 10.2210/pdb1tp7/pdb |
Descriptor | Genome polyprotein, SULFATE ION, 3-[BENZYL(DIMETHYL)AMMONIO]PROPANE-1-SULFONATE, ... (4 entities in total) |
Functional Keywords | rhinovirus, rna, polymerase, 3d, transferase |
Biological source | Human rhinovirus 16 |
Cellular location | Protein VP2: Virion. Protein VP3: Virion. Protein VP1: Virion. Protein 2B: Host cytoplasmic vesicle membrane; Peripheral membrane protein; Cytoplasmic side (Potential). Protein 2C: Host cytoplasmic vesicle membrane; Peripheral membrane protein; Cytoplasmic side (Potential). Protein 3A: Host cytoplasmic vesicle membrane; Peripheral membrane protein; Cytoplasmic side (Potential). Protein 3B: Virion (Potential). Picornain 3C: Host cytoplasm (Potential). RNA-directed RNA polymerase 3D-POL: Host cytoplasmic vesicle membrane; Peripheral membrane protein; Cytoplasmic side (Potential): Q82122 |
Total number of polymer chains | 4 |
Total formula weight | 211893.52 |
Authors | Appleby, T.C.,Luecke, H.,Shim, J.H.,Wu, J.Z.,Cheney, I.W.,Zhong, W.,Vogeley, L.,Hong, Z.,Yao, N. (deposition date: 2004-06-15, release date: 2005-06-21, Last modification date: 2011-07-13) |
Primary citation | Appleby, T.C.,Luecke, H.,Shim, J.H.,Wu, J.Z.,Cheney, I.W.,Zhong, W.,Vogeley, L.,Hong, Z.,Yao, N. Crystal structure of complete rhinovirus RNA polymerase suggests front loading of protein primer. J.Virol., 79:277-288, 2005 Cited by PubMed: 15596823DOI: 10.1128/JVI.79.1.277-288.2005 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.4 Å) |
Structure validation
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