1TP7

Crystal Structure of the RNA-dependent RNA Polymerase from Human Rhinovirus 16

1TP7 の概要

分子名称Genome polyprotein, SULFATE ION, 3-[BENZYL(DIMETHYL)AMMONIO]PROPANE-1-SULFONATE, ... (4 entities in total)
機能のキーワードrhinovirus, rna, polymerase, 3d, transferase
由来する生物種Human rhinovirus 16
細胞内の位置Protein VP2: Virion. Protein VP3: Virion. Protein VP1: Virion. Protein 2B: Host cytoplasmic vesicle membrane; Peripheral membrane protein; Cytoplasmic side (Potential). Protein 2C: Host cytoplasmic vesicle membrane; Peripheral membrane protein; Cytoplasmic side (Potential). Protein 3A: Host cytoplasmic vesicle membrane; Peripheral membrane protein; Cytoplasmic side (Potential). Protein 3B: Virion (Potential). Picornain 3C: Host cytoplasm (Potential). RNA-directed RNA polymerase 3D-POL: Host cytoplasmic vesicle membrane; Peripheral membrane protein; Cytoplasmic side (Potential) Q82122
ポリマー鎖数4
分子量合計211893.52
構造登録者
Appleby, T.C.,Luecke, H.,Shim, J.H.,Wu, J.Z.,Cheney, I.W.,Zhong, W.,Vogeley, L.,Hong, Z.,Yao, N. (登録日: 2004-06-15, 公開日: 2005-06-21, 最終更新日: 2011-07-13)
主引用文献
Appleby, T.C.,Luecke, H.,Shim, J.H.,Wu, J.Z.,Cheney, I.W.,Zhong, W.,Vogeley, L.,Hong, Z.,Yao, N.
Crystal structure of complete rhinovirus RNA polymerase suggests front loading of protein primer.
J.Virol., 79:277-288, 2005
PubMed: 15596823 (主引用文献が同じPDBエントリー)
DOI: 10.1128/JVI.79.1.277-288.2005
MImport into Mendeley
実験手法
X-RAY DIFFRACTION (2.4 Å)
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構造検証レポート

ClashscoreRamachandran outliersSidechain outliers151.6%3.5%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution
検証レポート(詳細版)をダウンロード