1TOU

Crystal structure of human adipocyte fatty acid binding protein in complex with a non-covalent ligand

Summary for 1TOU

• Entry DOI: 10.2210/pdb1tou/pdb
• Related: 1TOW
• Descriptor: Fatty acid-binding protein, adipocyte, 2-[(2-OXO-2-PIPERIDIN-1-YLETHYL)SULFANYL]-6-(TRIFLUOROMETHYL)PYRIMIDIN-4-OL (3 entities in total)
• Functional Keywords: transport, lipid-binding, lipid transport
• Biological source: Homo sapiens (human)
• Cellular location: Cytoplasm: P15090
• Total number of polymer chains: 1
• Total formula weight: 14930.02

Authors

Ringom, R.,Axen, E.,Uppenberg, J.,Lundback, T.,Rondahl, L.,Barf, T. (deposition date: 2004-06-15, release date: 2004-08-24, Last modification date: 2024-03-13)

• Primary citation: Ringom, R.,Axen, E.,Uppenberg, J.,Lundback, T.,Rondahl, L.,Barf, T.; Substituted benzylamino-6-(trifluoromethyl)pyrimidin-4(1H)-ones: a novel class of selective human A-FABP inhibitors.; Bioorg.Med.Chem.Lett., 14:4449-4452, 2004; PubMed: 15357970; DOI: 10.1016/j.bmcl.2004.06.058

Experimental method

X-RAY DIFFRACTION (2 Å)