1TK3

Crystal Structure Of Human Apo Dipeptidyl Peptidase IV/CD26

Summary for 1TK3

• Entry DOI: 10.2210/pdb1tk3/pdb
• Related: 1TKR 1TO7
• Descriptor: Dipeptidyl peptidase IV, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... (8 entities in total)
• Functional Keywords: alpha/beta hydrolase, beta-propeller, homodimer, hydrolase
• Biological source: Homo sapiens (human)
• Total number of polymer chains: 2
• Total formula weight: 175182.11

Authors

Bjelke, J.R.,Christensen, J.,Branner, S.,Wagtmann, N.,Olsen, C.,Kanstrup, A.B.,Rasmussen, H.B. (deposition date: 2004-06-08, release date: 2004-07-06, Last modification date: 2023-08-23)

• Primary citation: Bjelke, J.R.,Christensen, J.,Branner, S.,Wagtmann, N.,Olsen, C.,Kanstrup, A.B.,Rasmussen, H.B.; Tyrosine 547 Constitutes an Essential Part of the Catalytic Mechanism of Dipeptidyl Peptidase IV; J.Biol.Chem., 279:34691-34697, 2004; PubMed: 15175333; DOI: 10.1074/jbc.M405400200

Experimental method

X-RAY DIFFRACTION (2 Å)