1TIJ

3D Domain-swapped human cystatin C with amyloid-like intermolecular beta-sheets

Summary for 1TIJ

Entry DOI	10.2210/pdb1tij/pdb
Related	1A67 1CEW 1DVC 1G96 1N9J 1R4C 1RN7 1STF
Descriptor	Cystatin C (2 entities in total)
Functional Keywords	human cystatin c dimer, 3d domain swapping, amyloid formation, inhibitor of c1 and c13 cysteine proteases, amyloid angiopathy, cerebral hemorrhage, hydrolase inhibitor
Biological source	Homo sapiens (human)
Cellular location	Secreted: P01034
Total number of polymer chains	2
Total formula weight	26730.28
Authors	Janowski, R.,Kozak, M.,Abrahamson, M.,Grubb, A.,Jaskolski, M. (deposition date: 2004-06-02, release date: 2005-07-19, Last modification date: 2023-08-23)
Primary citation	Janowski, R.,Kozak, M.,Abrahamson, M.,Grubb, A.,Jaskolski, M. 3D domain-swapped human cystatin C with amyloidlike intermolecular beta-sheets. Proteins, 61:570-578, 2005 Cited by PubMed: 16170782 DOI: 10.1002/prot.20633 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (3.03 Å)

Structure validation