1THS
STRUCTURES OF THROMBIN COMPLEXES WITH A DESIGNED AND A NATURAL EXOSITE INHIBITOR
Summary for 1THS
Entry DOI | 10.2210/pdb1ths/pdb |
Descriptor | ALPHA-THROMBIN (SMALL SUBUNIT), ALPHA-THROMBIN (LARGE SUBUNIT), SYNTHETIC INHIBITOR, ... (4 entities in total) |
Functional Keywords | serine proteinase, hydrolase-hydrolase inhibitor complex, hydrolase/hydrolase inhibitor |
Biological source | Homo sapiens (human) More |
Cellular location | Secreted, extracellular space: P00734 P00734 |
Total number of polymer chains | 3 |
Total formula weight | 35206.16 |
Authors | Qiu, X.,Yin, M.,Padmanabhan, K.P.,Krstenansky, J.L.,Tulinsky, A. (deposition date: 1993-06-16, release date: 1994-01-31, Last modification date: 2011-07-13) |
Primary citation | Qiu, X.,Yin, M.,Padmanabhan, K.P.,Krstenansky, J.L.,Tulinsky, A. Structures of thrombin complexes with a designed and a natural exosite peptide inhibitor. J.Biol.Chem., 268:20318-20326, 1993 Cited by PubMed: 8376390PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.2 Å) |
Structure validation
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