1TDL

Structure of Ser130Gly SHV-1 beta-lactamase

Summary for 1TDL

Entry DOI	10.2210/pdb1tdl/pdb
Related	1G56 1RCJ 1SHV 1TDG
Descriptor	Beta-lactamase SHV-1, CYCLOHEXYL-HEXYL-BETA-D-MALTOSIDE, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, ... (4 entities in total)
Functional Keywords	class a beta-lactamase, penicillinase, beta-lactam hydrolase, detergent binding, drug design, hydrolase
Biological source	Klebsiella pneumoniae
Total number of polymer chains	1
Total formula weight	30132.50
Authors	Sun, T.,Bethel, C.R.,Bonomo, R.A.,Knox, J.R. (deposition date: 2004-05-23, release date: 2004-11-23, Last modification date: 2023-08-23)
Primary citation	Sun, T.,Bethel, C.R.,Bonomo, R.A.,Knox, J.R. Inhibitor-resistant class A beta-lactamases: consequences of the Ser130-to-Gly mutation seen in Apo and tazobactam structures of the SHV-1 variant Biochemistry, 43:14111-14117, 2004 Cited by PubMed: 15518561 DOI: 10.1021/bi0487903 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.8 Å)

Structure validation