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1TDG

Complex of S130G SHV-1 beta-lactamase with tazobactam

Summary for 1TDG
Entry DOI10.2210/pdb1tdg/pdb
Related1G56 1RCJ 1SHV 1TDL
DescriptorBeta-lactamase SHV-1, CYCLOHEXYL-HEXYL-BETA-D-MALTOSIDE, TAZOBACTAM INTERMEDIATE, ... (7 entities in total)
Functional Keywordss130g shv-1 class a beta-lactamase, penicillinase, beta-lactam hydrolase, detergent binding, inhibitor complex, tazobactam, aldehyde, cymal-6, hydrolase
Biological sourceKlebsiella pneumoniae
Total number of polymer chains1
Total formula weight30504.91
Authors
Sun, T.,Bethel, C.R.,Bonomo, R.A.,Knox, J.R. (deposition date: 2004-05-21, release date: 2004-11-23, Last modification date: 2023-08-23)
Primary citationSun, T.,Bethel, C.R.,Bonomo, R.A.,Knox, J.R.
Inhibitor-resistant class A beta-lactamases: consequences of the Ser130-to-Gly mutation seen in Apo and tazobactam structures of the SHV-1 variant
Biochemistry, 43:14111-14117, 2004
Cited by
PubMed: 15518561
DOI: 10.1021/bi0487903
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (1.8 Å)
Structure validation

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