1TDG
Complex of S130G SHV-1 beta-lactamase with tazobactam
Summary for 1TDG
Entry DOI | 10.2210/pdb1tdg/pdb |
Related | 1G56 1RCJ 1SHV 1TDL |
Descriptor | Beta-lactamase SHV-1, CYCLOHEXYL-HEXYL-BETA-D-MALTOSIDE, TAZOBACTAM INTERMEDIATE, ... (7 entities in total) |
Functional Keywords | s130g shv-1 class a beta-lactamase, penicillinase, beta-lactam hydrolase, detergent binding, inhibitor complex, tazobactam, aldehyde, cymal-6, hydrolase |
Biological source | Klebsiella pneumoniae |
Total number of polymer chains | 1 |
Total formula weight | 30504.91 |
Authors | Sun, T.,Bethel, C.R.,Bonomo, R.A.,Knox, J.R. (deposition date: 2004-05-21, release date: 2004-11-23, Last modification date: 2023-08-23) |
Primary citation | Sun, T.,Bethel, C.R.,Bonomo, R.A.,Knox, J.R. Inhibitor-resistant class A beta-lactamases: consequences of the Ser130-to-Gly mutation seen in Apo and tazobactam structures of the SHV-1 variant Biochemistry, 43:14111-14117, 2004 Cited by PubMed: 15518561DOI: 10.1021/bi0487903 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.8 Å) |
Structure validation
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