1TD7
Interactions of a specific non-steroidal anti-inflammatory drug (NSAID) with group I phospholipase A2 (PLA2): Crystal structure of the complex formed between PLA2 and niflumic acid at 2.5 A resolution
Summary for 1TD7
Entry DOI | 10.2210/pdb1td7/pdb |
Related | 1MF4 |
Descriptor | Phospholipase A2 isoform 3, CALCIUM ION, 2-{[3-(TRIFLUOROMETHYL)PHENYL]AMINO}NICOTINIC ACID, ... (4 entities in total) |
Functional Keywords | phospholipase a2, enzyme, inhibitor, hydrolase |
Biological source | Naja sagittifera |
Cellular location | Secreted: P60045 |
Total number of polymer chains | 1 |
Total formula weight | 13505.89 |
Authors | Jabeen, T.,Singh, N.,Singh, R.K.,Sharma, S.,Perbandt, M.,Betzel, C.,Singh, T.P. (deposition date: 2004-05-21, release date: 2004-06-08, Last modification date: 2023-10-25) |
Primary citation | Jabeen, T.,Singh, N.,Singh, R.K.,Sharma, S.,Somvanshi, R.K.,Dey, S.,Singh, T.P. Non-steroidal anti-inflammatory drugs as potent inhibitors of phospholipase A2: structure of the complex of phospholipase A2 with niflumic acid at 2.5 Angstroms resolution. Acta Crystallogr.,Sect.D, 61:1579-1586, 2005 Cited by PubMed: 16301791DOI: 10.1107/S0907444905029604 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.5 Å) |
Structure validation
Download full validation report