1TC2

TERNARY SUBSTRATE COMPLEX OF THE HYPOXANTHINE PHOSPHORIBOSYLTRANSFERASE FROM TRYPANOSOMA CRUZI

1TC2 の概要

• エントリーDOI: 10.2210/pdb1tc2/pdb
• 分子名称: PROTEIN (HYPOXANTHINE PHOSPHORIBOSYLTRANSFERASE), MAGNESIUM ION, 7-HYDROXY-PYRAZOLO[4,3-D]PYRIMIDINE, ... (6 entities in total)
• 機能のキーワード: transferase, glycosyltransferase, phosphoribosyltransferase, nucleotide metabolism, purine salvage, ternary complex, near transition state
• 由来する生物種: Trypanosoma cruzi
• 細胞内の位置: Cytoplasm : Q27796
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 52371.02

構造登録者

Focia, P.J.,Craig III, S.P.,Eakin, A.E. (登録日: 1998-11-04, 公開日: 2000-03-08, 最終更新日: 2023-08-23)

• 主引用文献: Focia, P.J.,Craig III, S.P.,Eakin, A.E.; Approaching the transition state in the crystal structure of a phosphoribosyltransferase.; Biochemistry, 37:17120-17127, 1998; PubMed: 9860824; DOI: 10.1021/bi9821465

実験手法

X-RAY DIFFRACTION (1.81 Å)