1T7H

X-ray structure of [Lys(-2)-Arg(-1)-des(17-21)]-endothelin-1 peptide

Summary for 1T7H

• Entry DOI: 10.2210/pdb1t7h/pdb
• Descriptor: Endothelin-1 (2 entities in total)
• Functional Keywords: endothelin, dimer, salt bridge, cysteine stabilized helical motif, signaling protein
• Biological source: Homo sapiens (human)
• Cellular location: Secreted: P05305
• Total number of polymer chains: 2
• Total formula weight: 4287.11

Authors

Hoh, F.,Cerdan, R.,Kaas, Q.,Nishi, Y.,Chiche, L.,Kubo, S.,Chino, N.,Kobayashi, Y.,Dumas, C.,Aumelas, A. (deposition date: 2004-05-10, release date: 2004-12-21, Last modification date: 2017-10-11)

• Primary citation: Hoh, F.,Cerdan, R.,Kaas, Q.,Nishi, Y.,Chiche, L.,Kubo, S.,Chino, N.,Kobayashi, Y.,Dumas, C.,Aumelas, A.; High-resolution X-ray structure of the unexpectedly stable dimer of the [Lys(-2)-Arg(-1)-des(17-21)]endothelin-1 peptide; Biochemistry, 43:15154-15168, 2004; PubMed: 15568807; DOI: 10.1021/bi049098a

Experimental method

X-RAY DIFFRACTION (1.13 Å)