1T6S

Crystal structure of a conserved hypothetical protein from Chlorobium tepidum

1T6S の概要

• エントリーDOI: 10.2210/pdb1t6s/pdb
• 分子名称: conserved hypothetical protein, NITRATE ION (3 entities in total)
• 機能のキーワード: a winged helix-turn-helix, structural genomics, bsgc structure funded by nih, protein structure initiative, psi, berkeley structural genomics center, unknown function
• 由来する生物種: Chlorobium tepidum TLS
• 細胞内の位置: Cytoplasm (By similarity): Q8KF54
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 38256.07

構造登録者

Kim, J.S.,Shin, D.H.,Kim, R.,Kim, S.H.,Berkeley Structural Genomics Center (BSGC) (登録日: 2004-05-07, 公開日: 2004-12-07, 最終更新日: 2024-02-14)

主引用文献

Kim, J.S.,Shin, D.H.,Pufan, R.,Huang, C.,Yokota, H.,Kim, R.,Kim, S.H.
Crystal structure of ScpB from Chlorobium tepidum, a protein involved in chromosome partitioning.
Proteins, 62:322-328, 2006

PubMed Abstract: Structural maintenance of chromosome (SMC) proteins are essential in chromosome condensation and interact with non-SMC proteins in eukaryotes and with segregation and condensation proteins (ScpA and ScpB) in prokaryotes. The highly conserved gene in Chlorobium tepidum gi 21646405 encodes ScpB (ScpB_ChTe). The high resolution crystal structure of ScpB_ChTe shows that the monomeric structure consists of two similarly shaped globular domains composed of three helices sided by beta-strands [a winged helix-turn-helix (HTH)], a motif observed in the C-terminal domain of Scc1, a functionally related eukaryotic ScpA homolog, as well as in many DNA binding proteins.

PubMed: 16294331
DOI: 10.1002/prot.20751

実験手法

X-RAY DIFFRACTION (1.95 Å)