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1T2E

Plasmodium falciparum lactate dehydrogenase S245A, A327P mutant complexed with NADH and oxamate

Summary for 1T2E
Entry DOI10.2210/pdb1t2e/pdb
Related1LDG 1T24 1T25 1T26 1T2C 1T2D 1T2F
DescriptorL-lactate dehydrogenase, 1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE, OXAMIC ACID, ... (5 entities in total)
Functional Keywordsternary complex, oxidoreductase
Biological sourcePlasmodium falciparum (malaria parasite P. falciparum)
Total number of polymer chains1
Total formula weight35834.21
Authors
Primary citationCameron, A.,Read, J.,Tranter, R.,Winter, V.J.,Sessions, R.B.,Brady, R.L.,Vivas, L.,Easton, A.,Kendrick, H.,Croft, S.L.,Barros, D.,Lavandera, J.L.,Martin, J.J.,Risco, F.,Garcia-Ochoa, S.,Gamo, F.J.,Sanz, L.,Leon, L.,Ruiz, J.R.,Gabarro, R.,Mallo, A.,De Las Heras, F.G.
Identification and Activity of a Series of Azole-based Compounds with Lactate Dehydrogenase-directed Anti-malarial Activity.
J.Biol.Chem., 279:31429-31439, 2004
Cited by
PubMed: 15117937
DOI: 10.1074/jbc.M402433200
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (1.85 Å)
Structure validation

217705

数据于2024-03-27公开中

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