1T2E
Plasmodium falciparum lactate dehydrogenase S245A, A327P mutant complexed with NADH and oxamate
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | L-lactate dehydrogenase | polymer | 322 | 34987.6 | 1 | UniProt (Q27743) Pfam (PF00056) Pfam (PF02866) | Plasmodium falciparum (malaria parasite P. falciparum) | LDH-P |
| 2 | B (A) | 1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE | non-polymer | 665.4 | 1 | Chemie (NAI) | |||
| 3 | C (A) | OXAMIC ACID | non-polymer | 89.0 | 1 | Chemie (OXM) | |||
| 4 | D (A) | GLYCEROL | non-polymer | 92.1 | 1 | Chemie (GOL) | |||
| 5 | E (A) | water | water | 18.0 | 242 | Chemie (HOH) |
Sequence modifications
A: 17 - 329 (UniProt: Q27743)
| PDB | External Database | Details |
|---|---|---|
| Ala 245 | Ser 234 | engineered mutation |
| Pro 327 | Ala 314 | engineered mutation |
| His 330 | - | expression tag |
| His 331 | - | expression tag |
| His 332 | - | expression tag |
| His 333 | - | expression tag |
| His 334 | - | expression tag |
| His 335 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 34987.6 | |
| Non-Polymers* | Number of molecules | 3 |
| Total formula weight | 846.6 | |
| All* | Total formula weight | 35834.2 |
