1SYH

X-RAY STRUCTURE OF THE GLUR2 LIGAND-BINDING CORE (S1S2J) IN COMPLEX WITH (S)-CPW399 AT 1.85 A RESOLUTION.

1SYH の概要

• エントリーDOI: 10.2210/pdb1syh/pdb
• 関連するPDBエントリー: 1ftj 1ftm 1fw0 1gr2 1m5b 1m5c 1m5e 1mqd 1mqg 1nnp 1SYI
• 分子名称: Glutamate receptor 2, (S)-2-AMINO-3-(1,3,5,7-PENTAHYDRO-2,4-DIOXO-CYCLOPENTA[E]PYRIMIDIN-1-YL) PROIONIC ACID (3 entities in total)
• 機能のキーワード: ionotropic glutamate receptor glur2, ligand-binding core, agonist complex, membrane protein
• 由来する生物種: Rattus norvegicus (Norway rat)
• 細胞内の位置: Cell membrane; Multi-pass membrane protein: P19491
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 29460.91

構造登録者

Frandsen, A.,Pickering, D.S.,Vestergaard, B.,Kasper, C.,Nielsen, B.B.,Greenwood, J.R.,Campiani, G.,Gajhede, M.,Schousboe, A.,Kastrup, J.S. (登録日: 2004-04-01, 公開日: 2005-03-22, 最終更新日: 2023-08-23)

• 主引用文献: Frandsen, A.,Pickering, D.S.,Vestergaard, B.,Kasper, C.,Nielsen, B.B.,Greenwood, J.R.,Campiani, G.,Fattorusso, C.,Gajhede, M.,Schousboe, A.,Kastrup, J.S.; Tyr702 Is an Important Determinant of Agonist Binding and Domain Closure of the Ligand-Binding Core of GluR2.; Mol.Pharmacol., 67:703-713, 2005; PubMed: 15591246; DOI: 10.1124/mol.104.002931

実験手法

X-RAY DIFFRACTION (1.8 Å)