1SUX

CRYSTALLOGRAPHIC ANALYSIS OF THE COMPLEX BETWEEN TRIOSEPHOSPHATE ISOMERASE FROM TRYPANOSOMA CRUZI AND 3-(2-benzothiazolylthio)-1-propanesulfonic acid

Summary for 1SUX

Entry DOI	10.2210/pdb1sux/pdb
Descriptor	Triosephosphate isomerase, glycosomal, SULFATE ION, 3-(2-BENZOTHIAZOLYLTHIO)-1-PROPANESULFONIC ACID, ... (4 entities in total)
Functional Keywords	triosephosphate isomerase, trypanosoma cruzi, protein interfaces, benzothiazole inhibitor, isomerase
Biological source	Trypanosoma cruzi
Cellular location	Glycosome: P52270
Total number of polymer chains	2
Total formula weight	55682.71
Authors	Tellez-Valencia, A.,Olivares-Illana, V.,Hernandez-Santoyo, A.,Perez-Montfort, R.,Costas, M.,Rodriguez-Romero, A.,Tuena De Gomez-Puyou, M.,Gomez-Puyou, A. (deposition date: 2004-03-26, release date: 2004-08-24, Last modification date: 2023-08-23)
Primary citation	Tellez-Valencia, A.,Olivares-Illana, V.,Hernandez-Santoyo, A.,Perez-Montfort, R.,Costas, M.,Rodriguez-Romero, A.,Lopez-Calahorra, F.,Tuena De Gomez-Puyou, M.,Gomez-Puyou, A. Inactivation of triosephosphate isomerase from Trypanosoma cruzi by an agent that perturbs its dimer interface. J.Mol.Biol., 341:1355-1365, 2004 Cited by PubMed: 15321726 DOI: 10.1016/j.jmb.2004.06.056 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2 Å)

Structure validation