1STH

TWO DISTINCTLY DIFFERENT METAL BINDING MODES ARE SEEN IN X-RAY CRYSTAL STRUCTURES OF STAPHYLOCOCCAL NUCLEASE-COBALT(II)-NUCLEOTIDE COMPLEXES

1STH の概要

• エントリーDOI: 10.2210/pdb1sth/pdb
• 分子名称: STAPHYLOCOCCAL NUCLEASE, COBALT (II) ION, THYMIDINE-3',5'-DIPHOSPHATE, ... (4 entities in total)
• 機能のキーワード: hydrolase (phosphoric diester)
• 由来する生物種: Staphylococcus aureus
• 細胞内の位置: Nuclease A: Secreted. Nuclease B: Membrane: P00644
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 17304.45

構造登録者

Loll, P.J.,Quirk, S.,Lattman, E.E. (登録日: 1994-10-27, 公開日: 1995-02-27, 最終更新日: 2024-02-14)

• 主引用文献: Loll, P.J.,Quirk, S.,Lattman, E.E.,Garavito, R.M.; X-ray crystal structures of staphylococcal nuclease complexed with the competitive inhibitor cobalt(II) and nucleotide.; Biochemistry, 34:4316-4324, 1995; PubMed: 7703245; DOI: 10.1021/bi00013a021

実験手法

X-RAY DIFFRACTION (1.85 Å)