1STC
CAMP-DEPENDENT PROTEIN KINASE, ALPHA-CATALYTIC SUBUNIT IN COMPLEX WITH STAUROSPORINE
Summary for 1STC
Entry DOI | 10.2210/pdb1stc/pdb |
Descriptor | CAMP-DEPENDENT PROTEIN KINASE, PROTEIN KINASE INHIBITOR, STAUROSPORINE, ... (4 entities in total) |
Functional Keywords | protein kinase, staurosporine, camp, phosphorylation, complex (transferase-inhibitor), serine/threonine-protein kinase, complex (transferase-inhibitor) complex, complex (transferase/inhibitor) |
Biological source | Bos taurus (cattle) |
Cellular location | Cytoplasm: P00517 |
Total number of polymer chains | 2 |
Total formula weight | 43479.34 |
Authors | Prade, L.,Engh, R.A.,Girod, A.,Kinzel, V.,Huber, R.,Bossemeyer, D. (deposition date: 1997-10-10, release date: 1998-02-25, Last modification date: 2023-08-09) |
Primary citation | Prade, L.,Engh, R.A.,Girod, A.,Kinzel, V.,Huber, R.,Bossemeyer, D. Staurosporine-induced conformational changes of cAMP-dependent protein kinase catalytic subunit explain inhibitory potential. Structure, 5:1627-1637, 1997 Cited by PubMed: 9438863DOI: 10.1016/S0969-2126(97)00310-9 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.3 Å) |
Structure validation
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