1STC

CAMP-DEPENDENT PROTEIN KINASE, ALPHA-CATALYTIC SUBUNIT IN COMPLEX WITH STAUROSPORINE

Summary for 1STC

DescriptorCAMP-DEPENDENT PROTEIN KINASE, PROTEIN KINASE INHIBITOR, STAUROSPORINE, ... (4 entities in total)
Functional Keywordsprotein kinase, staurosporine, camp, phosphorylation, complex (transferase-inhibitor), serine/threonine-protein kinase, complex (transferase-inhibitor) complex, complex (transferase/inhibitor)
Biological sourceBos taurus (cattle)
Cellular locationCytoplasm P00517
Total number of polymer chains2
Total molecular weight43479.34
Authors
Prade, L.,Engh, R.A.,Girod, A.,Kinzel, V.,Huber, R.,Bossemeyer, D. (deposition date: 1997-10-10, release date: 1998-02-25, Last modification date: 2011-07-13)
Primary citation
Prade, L.,Engh, R.A.,Girod, A.,Kinzel, V.,Huber, R.,Bossemeyer, D.
Staurosporine-induced conformational changes of cAMP-dependent protein kinase catalytic subunit explain inhibitory potential.
Structure, 5:1627-1637, 1997
PubMed: 9438863 (PDB entries with the same primary citation)
DOI: 10.1016/S0969-2126(97)00310-9
MImport into Mendeley
Experimental method
X-RAY DIFFRACTION (2.3 Å)
NMR Information
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Structure validation

ClashscoreRamachandran outliersSidechain outliers361.4%20.5%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution