1SP5

Crystal structure of HIV-1 protease complexed with a product of autoproteolysis

Summary for 1SP5

• Entry DOI: 10.2210/pdb1sp5/pdb
• Descriptor: Protease, 5-mer peptide from Protease, CHLORIDE ION, ... (6 entities in total)
• Functional Keywords: product, autoproteolysis, self-digestion, autodigestion, aspartic protease, hiv, protease, complex(aspartic protease-peptide), hydrolase
• Biological source: Human immunodeficiency virus 1; More
• Cellular location: Matrix protein p17: Virion (Potential). Capsid protein p24: Virion (Potential). Nucleocapsid protein p7: Virion (Potential). Reverse transcriptase/ribonuclease H: Virion (Potential). Integrase: Virion (Potential): P03367 P03367
• Total number of polymer chains: 3
• Total formula weight: 22677.12

Authors

Vondrackova, E.,Hasek, J.,Jaskolski, M.,Rezacova, P.,Dohnalek, J.,Skalova, T.,Petrokova, H.,Duskova, J.,Brynda, J.,Sedlacek, J. (deposition date: 2004-03-16, release date: 2005-07-19, Last modification date: 2023-10-25)

• Primary citation: Vondrackova, E.,Hasek, J.,Jaskolski, M.,Rezacova, P.,Dohnalek, J.,Skalova, T.,Petrokova, H.,Duskova, J.,Brynda, J.,Sedlacek, J.; Product of enzymatic self-cleavage bound in the active site of HIV protease; To be Published,

Experimental method

X-RAY DIFFRACTION (1.8 Å)