1SOJ

CATALYTIC DOMAIN OF HUMAN PHOSPHODIESTERASE 3B IN COMPLEX WITH IBMX

Summary for 1SOJ

• Entry DOI: 10.2210/pdb1soj/pdb
• Related: 1SO2
• Descriptor: cGMP-inhibited 3',5'-cyclic phosphodiesterase B, MAGNESIUM ION, 3-ISOBUTYL-1-METHYLXANTHINE, ... (4 entities in total)
• Functional Keywords: pde3b phosphodiesterase, hydrolase
• Biological source: Homo sapiens (human)
• Cellular location: Membrane; Multi-pass membrane protein (Potential): Q13370
• Total number of polymer chains: 12
• Total formula weight: 581155.62

Authors

Scapin, G.,Patel, S.B.,Chung, C.,Varnerin, J.P.,Edmondson, S.D.,Mastracchio, A.,Parmee, E.R.,Becker, J.W.,Singh, S.B.,Van Der Ploeg, L.H.,Tota, M.R. (deposition date: 2004-03-15, release date: 2004-05-11, Last modification date: 2023-08-23)

• Primary citation: Scapin, G.,Patel, S.B.,Chung, C.,Varnerin, J.P.,Edmondson, S.D.,Mastracchio, A.,Parmee, E.R.,Singh, S.B.,Becker, J.W.,Van Der Ploeg, L.H.,Tota, M.R.; Crystal Structure of Human Phosphodiesterase 3B: Atomic Basis for Substrate and Inhibitor Specificity; Biochemistry, 43:6091-6100, 2004; PubMed: 15147193; DOI: 10.1021/bi049868i

Experimental method

X-RAY DIFFRACTION (2.9 Å)