1SLN

CRYSTAL STRUCTURE OF THE CATALYTIC DOMAIN OF HUMAN FIBROBLAST STROMELYSIN-1 INHIBITED WITH THE N-CARBOXY-ALKYL INHIBITOR L-702,842

1SLN の概要

• エントリーDOI: 10.2210/pdb1sln/pdb
• 分子名称: STROMELYSIN-1, ZINC ION, CALCIUM ION, ... (5 entities in total)
• 機能のキーワード: hydrolase, metalloprotease, fibroblast, collagen degradation
• 由来する生物種: Homo sapiens (human)
• 細胞内の位置: Secreted, extracellular space, extracellular matrix : P08254
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 20151.16

構造登録者

Becker, J.W. (登録日: 1995-08-03, 公開日: 1996-12-17, 最終更新日: 2024-02-14)

• 主引用文献: Becker, J.W.,Marcy, A.I.,Rokosz, L.L.,Axel, M.G.,Burbaum, J.J.,Fitzgerald, P.M.,Cameron, P.M.,Esser, C.K.,Hagmann, W.K.,Hermes, J.D.,Springer, J.P.; Stromelysin-1: three-dimensional structure of the inhibited catalytic domain and of the C-truncated proenzyme.; Protein Sci., 4:1966-1976, 1995; PubMed: 8535233

実験手法

X-RAY DIFFRACTION (2.27 Å)