1SIO

Structure of Kumamolisin-As complexed with a covalently-bound inhibitor, AcIPF

Summary for 1SIO

Related1SIU
Related PRD IDPRD_000240
Descriptorkumamolisin-As, Ace-ILE-PRO-PHL peptide inhibitor, SULFATE ION, ... (5 entities in total)
Functional Keywordskumamolisin-as, hydrolase-hydrolase inhibitor complex, hydrolase/hydrolase inhibitor
Biological sourceAlicyclobacillus sendaiensis
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Total number of polymer chains6
Total molecular weight111726.05
Authors
Li, M.,Wlodawer, A.,Gustchina, A.,Tsuruoka, N.,Ashida, M.,Minakata, H.,Oyama, H.,Oda, K.,Nishino, T.,Nakayama, T. (deposition date: 2004-03-01, release date: 2004-03-30, Last modification date: 2012-12-12)
Primary citation
Wlodawer, A.,Li, M.,Gustchina, A.,Tsuruoka, N.,Ashida, M.,Minakata, H.,Oyama, H.,Oda, K.,Nishino, T.,Nakayama, T.
Crystallographic and biochemical investigations of kumamolisin-As, a serine-carboxyl peptidase with collagenase activity
J.Biol.Chem., 279:21500-21510, 2004
PubMed: 15014068 (PDB entries with the same primary citation)
DOI: 10.1074/jbc.M401141200
MImport into Mendeley
Experimental method
X-RAY DIFFRACTION (1.8 Å)
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Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers0.2311008.5%1.5%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution