1SG1

Crystal Structure of the Receptor-Ligand Complex between Nerve Growth Factor and the Common Neurotrophin Receptor p75

1SG1 の概要

• エントリーDOI: 10.2210/pdb1sg1/pdb
• 分子名称: Beta-nerve growth factor, Tumor necrosis factor receptor superfamily member 16, CHLORIDE ION, ... (4 entities in total)
• 機能のキーワード: nerve growth factor, ngf, p75, neurotrophin, common neurotrophin receptor, growth factor receptor, receptor-ligand complex, hormone-growth factor-membrane protein complex, hormone/growth factor/membrane protein
• 由来する生物種: Homo sapiens (human); 詳細
• 細胞内の位置: Secreted: P01138; Membrane; Single-pass type I membrane protein: P07174
• タンパク質・核酸の鎖数: 3
• 化学式量合計: 44324.29

構造登録者

He, X.L.,Garcia, K.C. (登録日: 2004-02-22, 公開日: 2004-06-01, 最終更新日: 2023-08-23)

• 主引用文献: He, X.L.,Garcia, K.C.; Structure of nerve growth factor complexed with the shared neurotrophin receptor p75; Science, 304:870-875, 2004; PubMed: 15131306; DOI: 10.1126/science.1095190

実験手法

X-RAY DIFFRACTION (2.4 Å)