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1SC3

Crystal structure of the human caspase-1 C285A mutant in complex with malonate

Summary for 1SC3
Entry DOI10.2210/pdb1sc3/pdb
Related1SC4 1sc1
DescriptorInterleukin-1 beta convertase, MALONATE ION, ... (4 entities in total)
Functional Keywordsmalonate-bound caspase-1, hydrolase
Biological sourceHomo sapiens (human)
More
Cellular locationCytoplasm: P29466 P29466
Total number of polymer chains2
Total formula weight30198.57
Authors
Romanowski, M.J.,Scheer, J.M.,O'Brien, T.,McDowell, R.S. (deposition date: 2004-02-11, release date: 2004-08-10, Last modification date: 2023-08-23)
Primary citationRomanowski, M.J.,Scheer, J.M.,O'Brien, T.,McDowell, R.S.
Crystal structures of a ligand-free and malonate-bound human caspase-1: implications for the mechanism of substrate binding.
Structure, 12:1361-1371, 2004
Cited by
PubMed: 15296730
DOI: 10.1016/j.str.2004.05.010
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (1.8 Å)
Structure validation

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