1S9V
Crystal structure of HLA-DQ2 complexed with deamidated gliadin peptide
Summary for 1S9V
Entry DOI | 10.2210/pdb1s9v/pdb |
Descriptor | HLA class II histocompatibility antigen, DQ(3) alpha chain, HLA class II histocompatibility antigen, DQ(1) beta chain, alpha-I gliadin, ... (5 entities in total) |
Functional Keywords | immune system, hla-dq2 |
Biological source | Homo sapiens (human) More |
Cellular location | Cell membrane; Single-pass type I membrane protein: P01909 |
Total number of polymer chains | 6 |
Total formula weight | 92638.08 |
Authors | Kim, C.-Y.,Quarsten, H.,Bergseng, E.,Khosla, C.,Sollid, L.M. (deposition date: 2004-02-05, release date: 2004-03-02, Last modification date: 2011-07-13) |
Primary citation | Kim, C.-Y.,Quarsten, H.,Bergseng, E.,Khosla, C.,Sollid, L.M. Structural basis for HLA-DQ2-mediated presentation of gluten epitopes in celiac disease Proc.Natl.Acad.Sci.USA, 101:4175-4179, 2004 Cited by PubMed: 15020763DOI: 10.1073/pnas.0306885101 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.22 Å) |
Structure validation
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