1S8A

H98Q Mutant of Methylglyoxal Synthase from E. coli complexed with Phosphoglycolic Acid

Summary for 1S8A

• Entry DOI: 10.2210/pdb1s8a/pdb
• Related: 1S89
• Descriptor: Methylglyoxal synthase, 2-PHOSPHOGLYCOLIC ACID (3 entities in total)
• Functional Keywords: glycolytic bypass, methylglyoxal, lyase
• Biological source: Escherichia coli
• Cellular location: Cytoplasm: P0A731
• Total number of polymer chains: 6
• Total formula weight: 102501.34

Authors

Harrison, D.H.,Marks, G.T.,Susler, M. (deposition date: 2004-01-31, release date: 2004-03-30, Last modification date: 2024-02-14)

• Primary citation: Marks, G.T.,Susler, M.,Harrison, D.H.; Mutagenic studies on histidine 98 of methylglyoxal synthase: effects on mechanism and conformational change.; Biochemistry, 43:3802-3813, 2004; PubMed: 15049687; DOI: 10.1021/bi035838o

Experimental method

X-RAY DIFFRACTION (2.2 Å)