1S5O

Structural and Mutational Characterization of L-carnitine Binding to Human carnitine Acetyltransferase

1S5O の概要

• エントリーDOI: 10.2210/pdb1s5o/pdb
• 分子名称: carnitine acetyltransferase isoform 2, CARNITINE (3 entities in total)
• 機能のキーワード: carnitine acetyltransferase, binary complex, steady-state enzyme kinetics, substrate binding site, transferase
• 由来する生物種: Homo sapiens (human)
• 細胞内の位置: Endoplasmic reticulum (Potential). Isoform 1: Mitochondrion (Potential). Isoform 2: Peroxisome (Potential): P43155
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 70065.07

構造登録者

Govindasamy, L.,Kukar, T.,Lian, W.,Pedersen, B.,Gu, Y.,Agbandje-Mckenna, M.,Jin, S.,Mckenna, R.,Wu, D. (登録日: 2004-01-21, 公開日: 2004-02-03, 最終更新日: 2023-08-23)

• 主引用文献: Govindasamy, L.,Kukar, T.,Lian, W.,Pedersen, B.,Gu, Y.,Agbandje-McKenna, M.,Jin, S.,McKenna, R.,Wu, D.; Structural and mutational characterization of l-carnitine binding to human carnitine acetyltransferase.; J.Struct.Biol., 146:416-424, 2004; PubMed: 15099582; DOI: 10.1016/j.jsb.2004.01.011

実験手法

X-RAY DIFFRACTION (1.8 Å)