1S5L

Architecture of the photosynthetic oxygen evolving center

1S5L の概要

• エントリーDOI: 10.2210/pdb1s5l/pdb
• 関連するPDBエントリー: 1FE1 1IZL
• 分子名称: Photosystem Q(B) protein, Photosystem II reaction center protein K, Photosystem II reaction center L protein, ... (28 entities in total)
• 機能のキーワード: photosystem, photosynthesis, oxygen-evolving, tetra-manganese, membrane
• 由来する生物種: Thermosynechococcus elongatus; 詳細
• 細胞内の位置: Cellular thylakoid membrane; Multi-pass membrane protein: P0A444 Q8DHJ2; Cellular thylakoid membrane; Single-pass membrane protein: Q9F1K9 Q8DIN8 Q8DHA7 Q8DIQ0 Q8DIP0 Q8DIN9 Q8DJ43 Q8DJZ6; Cellular thylakoid membrane; Peripheral membrane protein; Lumenal side: Q9F1L5 P0A386; Cellular thylakoid membrane; Single-pass membrane protein (By similarity): Q9F1R6 P59087; Cellular thylakoid membrane; Multi-pass membrane protein (By similarity): Q8CM25
• タンパク質・核酸の鎖数: 38
• 化学式量合計: 692749.53

構造登録者

Ferreira, K.N.,Iverson, T.M.,Maghlaoui, K.,Barber, J.,Iwata, S. (登録日: 2004-01-21, 公開日: 2004-02-24, 最終更新日: 2024-12-25)

主引用文献

Ferreira, K.N.,Iverson, T.M.,Maghlaoui, K.,Barber, J.,Iwata, S.
Architecture of the Photosynthetic Oxygen-Evolving Center
Science, 303:1831-1838, 2004

PubMed Abstract: Photosynthesis uses light energy to drive the oxidation of water at an oxygen-evolving catalytic site within photosystem II (PSII). We report the structure of PSII of the cyanobacterium Thermosynechococcus elongatus at 3.5 angstrom resolution. We have assigned most of the amino acid residues of this 650-kilodalton dimeric multisubunit complex and refined the structure to reveal its molecular architecture. Consequently, we are able to describe details of the binding sites for cofactors and propose a structure of the oxygen-evolving center (OEC). The data strongly suggest that the OEC contains a cubane-like Mn3CaO4 cluster linked to a fourth Mn by a mono-micro-oxo bridge. The details of the surrounding coordination sphere of the metal cluster and the implications for a possible oxygen-evolving mechanism are discussed.

PubMed: 14764885
DOI: 10.1126/science.1093087

実験手法

X-RAY DIFFRACTION (3.5 Å)