1S4O

Crystal structure of yeast alpha1,2-mannosyltransferase Kre2p/Mnt1p: binary complex with GDP/Mn

Summary for 1S4O

• Entry DOI: 10.2210/pdb1s4o/pdb
• Descriptor: Glycolipid 2-alpha-mannosyltransferase, alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-alpha-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-alpha-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... (8 entities in total)
• Functional Keywords: alpha/beta fold, nucleotide-binding domain, rossmann fold, binary complex with gdp-mn2+, transferase
• Biological source: Saccharomyces cerevisiae (baker's yeast)
• Cellular location: Golgi apparatus membrane; Single-pass type II membrane protein: P27809
• Total number of polymer chains: 2
• Total formula weight: 86134.74

Authors

Lobsanov, Y.D.,Romero, P.A.,Sleno, B.,Yu, B.,Yip, P.,Herscovics, A.,Howell, P.L. (deposition date: 2004-01-16, release date: 2004-05-04, Last modification date: 2023-08-23)

• Primary citation: Lobsanov, Y.D.,Romero, P.A.,Sleno, B.,Yu, B.,Yip, P.,Herscovics, A.,Howell, P.L.; Structure of Kre2p/Mnt1p: A YEAST {alpha}1,2-MANNOSYLTRANSFERASE INVOLVED IN MANNOPROTEIN BIOSYNTHESIS; J.Biol.Chem., 279:17921-17931, 2004; PubMed: 14752117; DOI: 10.1074/jbc.M312720200

Experimental method

X-RAY DIFFRACTION (2.01 Å)