1RTD

STRUCTURE OF A CATALYTIC COMPLEX OF HIV-1 REVERSE TRANSCRIPTASE: IMPLICATIONS FOR NUCLEOSIDE ANALOG DRUG RESISTANCE

Summary for 1RTD
DescriptorDNA TEMPLATE FOR REVERSE TRANSCRIPTASE, DNA PRIMER FOR REVERSE TRANSCRIPTASE, PROTEIN (REVERSE TRANSCRIPTASE), ... (6 entities in total)
Functional Keywordscomplex(nucleotidyltransferase, dna, dntp), protein/dna, transferase-dna complex, transferase/dna
Biological sourceHuman immunodeficiency virus 1
More
Cellular locationMatrix protein p17: Virion (Potential). Capsid protein p24: Virion (Potential). Nucleocapsid protein p7: Virion (Potential). Reverse transcriptase/ribonuclease H: Virion (Potential). Integrase: Virion (Potential): P03366 P04585
Total number of polymer chains8
Total formula weight261133.52
Authors
Chopra, R.,Huang, H.,Verdine, G.L.,Harrison, S.C. (deposition date: 1998-08-26, release date: 1998-12-09, Last modification date: 2011-07-13)
Primary citationChopra, R.,Harrison, S.C.,Huang, H.,Verdine, G.L.
Structure of a covalently trapped catalytic complex of HIV-1 reverse transcriptase: implications for drug resistance.
Science, 282:1669-1675, 1998
PubMed: 9831551
DOI: 110.1126/science.282.5394.1669
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (3.2 Å)
Structure validation
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PDB entries from 2021-06-16