1RT6

HIV-1 REVERSE TRANSCRIPTASE COMPLEXED WITH UC38

1RT6 の概要

• エントリーDOI: 10.2210/pdb1rt6/pdb
• 分子名称: HIV-1 REVERSE TRANSCRIPTASE, PHOSPHATE ION, 1-METHYL ETHYL 2-CHLORO-5-[[[(1-METHYLETHOXY)THIOOXO]METHYL]AMINO]-BENZOATE, ... (5 entities in total)
• 機能のキーワード: nucleotidyltransferase, hiv-1 reverse transcriptase, aids, nonnucleoside inhibition, drug design
• 由来する生物種: HIV-1 M:B_HXB2R; 詳細
• 細胞内の位置: Matrix protein p17: Virion (Potential). Capsid protein p24: Virion (Potential). Nucleocapsid protein p7: Virion (Potential). Reverse transcriptase/ribonuclease H: Virion (Potential). Integrase: Virion (Potential): P04585 P04585
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 116404.78

構造登録者

Ren, J.,Stammers, D.K.,Stuart, D.I. (登録日: 1998-07-29, 公開日: 1999-07-29, 最終更新日: 2023-08-09)

• 主引用文献: Ren, J.,Esnouf, R.M.,Hopkins, A.L.,Warren, J.,Balzarini, J.,Stuart, D.I.,Stammers, D.K.; Crystal structures of HIV-1 reverse transcriptase in complex with carboxanilide derivatives.; Biochemistry, 37:14394-14403, 1998; PubMed: 9772165; DOI: 10.1021/bi981309m

実験手法

X-RAY DIFFRACTION (2.8 Å)