1RNE
THE CRYSTAL STRUCTURE OF RECOMBINANT GLYCOSYLATED HUMAN RENIN ALONE AND IN COMPLEX WITH A TRANSITION STATE ANALOG INHIBITOR
Summary for 1RNE
Entry DOI | 10.2210/pdb1rne/pdb |
Descriptor | RENIN, 2-acetamido-2-deoxy-beta-D-glucopyranose, [[[3-(2-METHYL-PROPANE-2-SULFONYL)-1-BENZENYL]-2-PROPYL]-CARBONYL-HISTIDYL]-AMINO-[CYCLOHEXYLMETHYL]-[2-HYDROXY-4-ISOPROPYL]-PENTAN-5-OIC ACID BUTYLAMIDE, ... (4 entities in total) |
Functional Keywords | hydrolase(acid proteinase) |
Biological source | Homo sapiens (human) |
Total number of polymer chains | 1 |
Total formula weight | 38218.23 |
Authors | Gruetter, M.G.,Rahuel, J.,Priestle, J.P. (deposition date: 1991-12-12, release date: 1993-10-31, Last modification date: 2020-10-21) |
Primary citation | Rahuel, J.,Priestle, J.P.,Grutter, M.G. The crystal structures of recombinant glycosylated human renin alone and in complex with a transition state analog inhibitor. J.Struct.Biol., 107:227-236, 1991 Cited by PubMed: 1807356DOI: 10.1016/1047-8477(91)90048-2 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.4 Å) |
Structure validation
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