1RBP

CRYSTALLOGRAPHIC REFINEMENT OF HUMAN SERUM RETINOL BINDING PROTEIN AT 2 ANGSTROMS RESOLUTION

1RBP の概要

• エントリーDOI: 10.2210/pdb1rbp/pdb
• 分子名称: PLASMA RETINOL-BINDING PROTEIN PRECURSOR, RETINOL (3 entities in total)
• 機能のキーワード: retinol transport
• 由来する生物種: Homo sapiens (human)
• 細胞内の位置: Secreted : P02753
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 21270.90

構造登録者

Jones, T.A.,Newcomer, M.E.,Cowan, S.W. (登録日: 1990-04-02, 公開日: 1991-07-15, 最終更新日: 2024-11-06)

主引用文献

Cowan, S.W.,Newcomer, M.E.,Jones, T.A.
Crystallographic refinement of human serum retinol binding protein at 2A resolution.
Proteins, 8:44-61, 1990

PubMed Abstract: Human serum retinol binding protein (RBP) in complex with retinol has been crystallographically refined to an R-factor of 18.1% with 2A resolution data. The protein topology results in an anti-parallel beta-barrel that encapsulates the retinol ligand. A detailed description of the protein and the binding site is provided. Our structural work has helped to define a family of proteins, many of which are carrier proteins for smaller ligand molecules. We describe the structural basis for the conservation of sequence within the family.

PubMed: 2217163
DOI: 10.1002/prot.340080108

実験手法

X-RAY DIFFRACTION (2 Å)