1R7M

The homing endonuclease I-SceI bound to its DNA recognition region

1R7M の概要

• エントリーDOI: 10.2210/pdb1r7m/pdb
• 分子名称: 5'-D(*CP*AP*CP*GP*CP*TP*AP*GP*GP*GP*AP*TP*AP*AP*CP*AP*GP*GP*GP*TP*AP*AP*TP*AP*C)-3', 5'-D(*GP*GP*TP*AP*TP*TP*AP*CP*CP*CP*TP*GP*TP*TP*AP*TP*CP*CP*CP*TP*AP*GP*CP*GP*T)-3', Intron-encoded endonuclease I-SceI, ... (5 entities in total)
• 機能のキーワード: protein-dna complex, endonuclease, laglidadg, beta-saddle, hydrolase-dna complex, hydrolase/dna
• 由来する生物種: Saccharomyces cerevisiae (baker's yeast)
• 細胞内の位置: Mitochondrion: P03882
• タンパク質・核酸の鎖数: 6
• 化学式量合計: 86388.78

構造登録者

Moure, C.M.,Gimble, F.S.,Quiocho, F.A. (登録日: 2003-10-21, 公開日: 2004-10-26, 最終更新日: 2024-02-14)

• 主引用文献: Moure, C.M.,Gimble, F.S.,Quiocho, F.A.; The crystal structure of the gene targeting homing endonuclease I-SceI reveals the origins of its target site specificity; J.Mol.Biol., 334:685-695, 2003; PubMed: 14636596; DOI: 10.1016/j.jmb.2003.09.068

実験手法

X-RAY DIFFRACTION (2.25 Å)