1R5W
Evidence that structural rearrangements and/or flexibility during TCR binding can contribute to T-cell activation
Summary for 1R5W
Entry DOI | 10.2210/pdb1r5w/pdb |
Descriptor | H-2 class II histocompatibility antigen, E-K alpha chain, MHC H2-IE-beta, artificial peptide (3 entities in total) |
Functional Keywords | tcr, mhc class ii, structural rearangement, signaling protein |
Biological source | Mus musculus (house mouse) More |
Cellular location | Membrane; Single-pass type I membrane protein (Potential): P04224 |
Total number of polymer chains | 6 |
Total formula weight | 88320.59 |
Authors | Krogsgaard, M.,Prado, N.,Adams, E.,He, X.,Chow, D.C.,Wilson, D.B.,Garcia, K.C.,Davis, M.M. (deposition date: 2003-10-13, release date: 2004-03-02, Last modification date: 2021-10-27) |
Primary citation | Krogsgaard, M.,Prado, N.,Adams, E.J.,He, X.L.,Chow, D.C.,Wilson, D.B.,Garcia, K.C.,Davis, M.M. Evidence that structural rearrangements and/or flexibility during TCR binding can contribute to T cell activation Mol.Cell, 12:1367-1378, 2003 Cited by PubMed: 14690592DOI: 10.1016/S1097-2765(03)00474-X PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.9 Å) |
Structure validation
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