1R5H
Crystal Structure of MetAP2 complexed with A320282
Summary for 1R5H
Entry DOI | 10.2210/pdb1r5h/pdb |
Related | 1R58 1R5G |
Descriptor | Methionine aminopeptidase 2, MANGANESE (II) ION, N'-(2S,3R)-3-AMINO-4-CYCLOHEXYL-2-HYDROXY-BUTANO-N-(4-METHYLPHENYL)HYDRAZIDE, ... (4 entities in total) |
Functional Keywords | hydrolase |
Biological source | Homo sapiens (human) |
Total number of polymer chains | 1 |
Total formula weight | 41785.29 |
Authors | Sheppard, G.S.,Wang, J.,Kawai, M.,BaMaung, N.Y.,Craig, R.A.,Erickson, S.A.,Lynch, L.,Patel, J.,Yang, F.,Searle, X.B.,Lou, P.,Park, C.,Kim, K.H.,Henkin, J.,Lesniewski, R. (deposition date: 2003-10-10, release date: 2004-10-12, Last modification date: 2011-07-13) |
Primary citation | Sheppard, G.S.,Wang, J.,Kawai, M.,BaMaung, N.Y.,Craig, R.A.,Erickson, S.A.,Lynch, L.,Patel, J.,Yang, F.,Searle, X.B.,Lou, P.,Park, C.,Kim, K.H.,Henkin, J.,Lesniewski, R. 3-Amino-2-hydroxyamides and related compounds as inhibitors of methionine aminopeptidase-2. Bioorg.Med.Chem.Lett., 14:865-868, 2004 Cited by PubMed: 15012983DOI: 10.1016/j.bmcl.2003.12.031 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.4 Å) |
Structure validation
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